RNA degradation drives stem cell differentiation
نویسندگان
چکیده
منابع مشابه
RNA degradation drives stem cell differentiation.
The mechanisms by which multi-potent stem cells switch their program to become functional differentiated cells have intrigued biologists for decades. Most focus has been on transcriptional pathways, but whether they have sufficient dynamic range to cause discrete shifts in cell state is not clear. Because the steady-state level of RNAs is also dictated by their decay rate, an attractive possibi...
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ژورنال
عنوان ژورنال: The EMBO Journal
سال: 2015
ISSN: 0261-4189,1460-2075
DOI: 10.15252/embj.201591631